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. 2026 Jan 15;15:e84240. doi: 10.2196/84240

Table 1.

Key questionnaires for all participants.

Category and concepts Measures
Pain and sensory symptoms

Multisite pain

  • Michigan Body Map (widespread pain index)

Symptom severity

  • Symptom Severity Score from the American College of Rheumatology 2016 fibromyalgia criteria

Neuropathic pain

  • painDETECT

  • Neuropathic Pain Symptom Inventory-Eye

Ocular surface symptoms

  • Ocular Surface Disease Index

Other chronic pain conditions with a nociplastic basis

  • Chronic overlapping pain condition screener

Chronic sensory symptoms

  • General Sensory Sensitivity Questionnaire-8

Photophobia

  • Visual Light Sensitivity Questionnaire-8

Pain duration and frequency

  • Two items adapted for the eye from the National Institutes of Health Research Task Force Minimum Dataset

Pain self-efficacy

  • Pain Self-Efficacy Questionnaire

Pain acceptance

  • Chronic Pain Acceptance Questionnaire

Pain catastrophizing

  • Pain Catastrophizing Scale

Pain interference, enjoyment, and general activity

  • Pain, Enjoyment of Life, and General Activity Scale-3

Pain interference-specific activity

  • PROMIS SFa version 1.0–Pain Interference 4a

Pain intensity

  • PROMIS SF version 2.0 0–Pain Intensity 3a

Pain severity

  • Pain Numeric Rating Scale
Nonpain central nervous system–mediated symptoms

Physical functioning or QoLb

  • PROMIS SF version 2.0–Physical Function 4a

Sleep

  • PROMIS SF version 1.0–Sleep Disturbance 4a

Depression

  • PROMIS SF version 1.0–Depression 4a

Anxiety

  • PROMIS SF version 1.0–Anxiety 4a

Fatigue

  • PROMIS SF version 1.0–Fatigue 4a

Social roles and activities

  • PROMIS SF version 2.0–Ability to Participate 4a

Memory and cognition

  • PROMIS SF version 2.0–Cognitive Function 4a

Sleep duration

  • Single item of sleep duration adapted from the Pittsburgh Sleep Quality Index

Dysautonomia

  • Composite Autonomic Symptom Score-31
QoL

Visual QoL

  • National Eye Institute Visual Functioning Questionnaire-9 and 2 pain subscale items

Overall QoL

  • World Health Organization Quality of Life-brief version
Social and psychological

Substance use

  • Tobacco, Alcohol, Prescription Medication, and other Substance Use tool

Optimism

  • Life Orientation Test-Revised

Trauma

  • Brief Trauma Questionnaire
Change measure

Impression of change

  • Patient Global Impression of Change scale

aPROMIS SF: Patient-Reported Outcomes Measurement Information System Short Form.

bQoL: quality of life.