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. 2026 Jan 19;55:101373. doi: 10.1016/j.lana.2026.101373

Table 2.

Binary logistic regression model of adjusted and unadjusted odds of using cannabis in the past 12 month and daily/near daily between 2018 and 2023 in Canadians reporting a mental health problem, or not, in the past 12 months (N = 91,907).

Mental health conditiona Past 12-month cannabis use % (n)c ADJUSTEDb Past 12-month use AOR (95% CI) p value Unadjusted past 12-month use OR (95% CI) p value Daily cannabis use % (n)d Adjusted daily use AOR (95% CI) p value Unadjusted daily use OR (95% CI) p value
Anxiety (n = 27,674)e
 2018 44.4% (1001) Reference Reference 17.7% (398) Reference Reference
 2019 50.5% (2096) 1.33 (1.15–1.53) <0.0001 1.28 (1.11–1.47) 0.0005 19.2% (797) 1.12 (0.93–1.36) 0.24 1.12 (0.93–1.35) 0.25
 2020 48.2% (2164) 1.27 (1.11–1.47) 0.0008 1.17 (1.02–1.34) 0.027 19.2% (863) 1.20 (0.99–1.45) 0.06 1.11 (0.92–1.34) 0.27
 2021 49.9% (2678) 1.37 (1.19–1.57) <0.0001 1.25 (1.09–1.43) 0.0012 21.0% (1127) 1.34 (1.11–1.61) 0.0019 1.24 (1.04–1.49) 0.017
 2022 47.1% (2404) 1.22 (1.07–1.40) 0.0043 1.12 (0.98–1.28) 0.10 18.4% (936) 1.15 (0.95–1.38) 0.15 1.05 (0.88–1.26) 0.58
 2023 46.3% (2982) 1.18 (1.03–1.34) 0.019 1.09 (0.95–1.24) 0.22 19.2% (1234) 1.19 (0.99–1.42) 0.07 1.11 (0.93–1.33) 0.24
Bipolar disorder (n = 3001)
 2018 63.4% (104) Reference Reference 32.8% (53) Reference Reference
 2019 63.1% (259) 1.05 (0.60–1.82) 0.87 0.99 (0.59–1.66) 0.96 31.3% (129) 1.00 (0.54–1.86) 1.00 0.93 (0.51–1.72) 0.83
 2020 55.4% (286) 0.80 (0.46–1.38) 0.42 0.72 (0.43–1.19) 0.20 24.2% (125) 0.74 (0.40–1.37) 0.33 0.65 (0.35–1.20) 0.17
 2021 58.7% (346) 0.87 (0.51–1.49) 0.62 0.82 (0.50–1.36) 0.45 28.4% (167) 0.94 (0.52–1.73) 0.85 0.82 (0.45–1.48) 0.51
 2022 56.5% (342) 0.83 (0.49–1.40) 0.48 0.75 (0.46–1.23) 0.26 29.8% (180) 1.02 (0.56–1.85) 0.94 0.87 (0.48–1.57) 0.65
 2023 63.9% (465) 1.21 (0.72–2.04) 0.47 1.03 (0.63–1.68) 0.91 30.1% (219) 1.07 (0.59–1.93) 0.82 0.89 (0.49–1.59) 0.68
Depression (n = 21,596)
 2018 45.2% (812) Reference Reference 18.8% (338) Reference Reference
 2019 54.0% (1728) 1.47 (1.26–1.73) <0.0001 1.42 (1.22–1.66) <0.0001 21.7% (695) 1.19 (0.96–1.46) 0.11 1.20 (0.98–1.47) 0.08
 2020 49.2% (1764) 1.28 (1.10–1.50) 0.0019 1.18 (1.01–1.38) 0.035 21.0% (753) 1.21 (0.98–1.49) 0.08 1.14 (0.93–1.40) 0.20
 2021 52.0% (2208) 1.43 (1.23–1.67) <0.0001 1.32 (1.14–1.53) 0.0003 23.4% (994) 1.37 (1.13–1.68) 0.0017 1.32 (1.09–1.60) 0.0053
 2022 49.6% (1943) 1.29 (1.11–1.50) 0.0011 1.19 (1.03–1.39) 0.020 20.8% (814) 1.18 (0.96–1.44) 0.11 1.13 (0.93–1.38) 0.22
 2023 48.8% (2400) 1.25 (1.07–1.45) 0.0040 1.16 (1.00–1.34) 0.05 20.5% (1008) 1.14 (0.94–1.39) 0.19 1.11 (0.92–1.35) 0.29
Post traumatic stress disorder (n = 6522)
 2018 55.8% (229) Reference Reference 27.8% (114) Reference Reference
 2019 61.3% (559) 1.34 (0.97–1.86) 0.08 1.26 (0.92–1.71) 0.15 30.3% (276) 1.18 (0.81–1.71) 0.38 1.13 (0.79–1.60) 0.51
 2020 57.1% (576) 1.18 (0.85–1.63) 0.32 1.05 (0.77–1.43) 0.75 26.0% (262) 0.99 (0.69–1.44) 0.97 0.90 (0.64–1.29) 0.58
 2021 58.0% (703) 1.18 (0.86–1.62) 0.30 1.09 (0.81–1.47) 0.56 30.9% (375) 1.26 (0.88–1.80) 0.21 1.17 (0.84–1.63) 0.37
 2022 52.7% (712) 1.04 (0.76–1.42) 0.79 0.89 (0.66–1.19) 0.42 25.4% (344) 1.04 (0.73–1.49) 0.83 0.89 (0.64–1.24) 0.48
 2023 56.1% (926) 1.15 (0.85–1.56) 0.37 1.02 (0.76–1.36) 0.92 24.8% (410) 0.94 (0.66–1.33) 0.71 0.86 (0.62–1.20) 0.37
Schizophrenia, including psychosis (n = 1882)
 2018 54.9% (64) Reference Reference 24.2% (28) Reference Reference
 2019 60.7% (113) 1.80 (0.86–3.79) 0.12 1.30 (0.65–2.57) 0.46 34.6% (64) 2.31 (0.97–5.52) 0.06 1.67 (0.75–3.75) 0.21
 2020 50.8% (147) 1.27 (0.63–2.57) 0.51 0.85 (0.44–1.63) 0.62 24.5% (71) 1.57 (0.67–3.66) 0.30 1.02 (0.46–2.25) 0.97
 2021 51.0% (193) 1.20 (0.62–2.34) 0.58 0.85 (0.46–1.59) 0.61 18.7% (71) 1.00 (0.44–2.30) 0.99 0.73 (0.34–1.57) 0.42
 2022 42.9% (175) 0.89 (0.46–1.70) 0.72 0.62 (0.33–1.14) 0.12 15.9% (65) 0.79 (0.35–1.79) 0.57 0.59 (0.27–1.27) 0.18
 2023 50.5% (257) 1.28 (0.66–2.46) 0.46 0.84 (0.46–1.55) 0.58 21.5% (109) 1.25 (0.57–2.78) 0.58 0.86 (0.41–1.81) 0.69
No experience of the mental health problems above (n = 56,239)f
 2018 20.8% (1465) Reference Reference 5.5% (391) Reference Reference
 2019 27.6% (2740) 1.52 (1.37–1.68) <0.0001 1.45 (1.31–1.60) <0.0001 7.4% (732) 1.34 (1.10–1.62) <0.0001 1.33 (1.10–1.61) 0.0031
 2020 26.4% (2558) 1.45 (1.31–1.62) <0.0001 1.37 (1.23–1.52) <0.0001 7.5% (722) 1.44 (1.18–1.75) <0.0001 1.36 (1.12–1.65) 0.0021
 2021 27.3% (2681) 1.55 (1.39–1.71) <0.0001 1.44 (1.30–1.59) <0.0001 9.1% (889) 1.79 (1.48–2.16) <0.0001 1.69 (1.40–2.03) <0.0001
 2022 27.6% (2514) 1.60 (1.44–1.78) <0.0001 1.45 (1.31–1.61) <0.0001 8.0% (727) 1.57 (1.29–1.90) <0.0001 1.45 (1.20–1.75) 0.0001
 2023 27.3% (3124) 1.58 (1.43–1.75) <0.0001 1.43 (1.30–1.58) <0.0001 8.0% (919) 1.58 (1.31–1.91) <0.0001 1.47 (1.22–1.77) <0.0001
a

Logistic regression models were stratified by mental health condition and including respondents who had experienced the condition in the past 12-months.

b

Adjusted for sex at birth, age group, ethnicity, education, province, and perceived income adequacy.

c

Past 12-month cannabis use is defined as any cannabis use in the past 12 months.

d

Daily cannabis use is defined as cannabis use on 5 or more days per week at the time of the survey.

e

Sample sizes for each mental health problem is the total sample size from 2018 through 2023.

f

No experience of anxiety, bipolar disorder, depression, post traumatic stress disorder, or schizophrenia/psychosis in the past 12 months.