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Comparison of response outcomes between hetrombopag monotherapy and combination regimens.
| Outcome | Hetrombopag (n = 28) | Hetrombopag-rhTPO/rhIL-11 (n = 45) | P |
|---|---|---|---|
| Primary outcome | |||
| 14-d response | 22 (78.6) | 36 (80.0) | .883 |
| Secondary outcome | |||
| 21-d response | 25 (89.3) | 42 (93.3) | .669 |
| Chemotherapy dose reduction/treatment delay | 4 (14.3) | 12 (26.7) | .214 |
| Median time to response, days (95% CI) | 9.0 (8.1-9.9) | 9.0 (7.9-10.1) | .640 |
rhIL, recombinant human interleukin; rhTPO, recombinant human thrombopoietin.
