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. 2025 Dec 17;6(2):101038. doi: 10.1016/j.xops.2025.101038

Table 4.

Pairwise Dice Similarity Coefficients (Mean ± SD) for Reticular Pseudodrusen Segmentation among 4 Ophthalmologists, ReticularNet, and Reading Center Ground Truth

Annotations Ophthalmologist 1 Ophthalmologist 2 Ophthalmologist 3 Ophthalmologist 4 ReticularNet Ground Truth
Ophthalmologist 1 - 0.19 ± 0.14 (0.01; 0.01) 0.03 ± 0.05 (0.33; 0.95) 0.13 ± 0.13 (0.03; 0.07) 0.18 ± 0.15 0.19 ± 0.15
Ophthalmologist 2 0.19 ± 0.14 (0.01; 0.01) - 0.02 ± 0.03 (0.6; 0.17) 0.14 ± 0.13 (0.02; 0.04) 0.21 ± 0.15 0.23 ± 0.14
Ophthalmologist 3 0.03 ± 0.05 (0.33; 0.95) 0.02 ± 0.03 (0.6; 0.17) - 0.02 ± 0.04 (0.23; 0.74) 0.03 ± 0.03 0.03 ± 0.04
Ophthalmologist 4 0.1 ± 0.13 (0.03; 0.07) 0.14 ± 0.13 (0.02; 0.04) 0.02 ± 0.04 (0.23; 0.74) - 0.13 ± 0.12 0.13 ± 0.13

SD = standard deviation.

Parentheses show paired Wilcoxon signed rank P values comparing each interophthalmologist Dice similarity coefficient distribution, first against that grader’s Dice similarity coefficient with the ground truth (first value) and then against that grader’s Dice similarity coefficient with ReticularNet (second value).