Skip to main content
. 2026 Jan 20;5(2):102536. doi: 10.1016/j.jacadv.2025.102536

Table 3.

Univariable and Multivariable Cox Regression Results for Risk of Recurrent Stroke

Covariate Univariable Model
Multivariable Model
HR 95% CI P Value Adjusted HR 95% CI P Value
Age 1.01 0.99–1.03 0.12 0.99 0.97–1.01 0.24
Female 0.80 0.55–1.17 0.25 0.57 0.38–0.85 0.005
AF 1.76 1.07–2.89 0.026 2.73 1.33–5.59 0.006
AF duration
 No AF/Unknown - - - - - -
 <6 min 1.04 0.45–2.39 0.92 0.56 0.22–1.41 0.22
 6 min–24 h 1.13 0.72–1.78 0.60 0.62 0.32–1.17 0.14
 >24 h 0.30 0.04–2.15 0.23 0.14 0.02–1.06 0.057
Index event
 Stroke - - - - - -
 TIA 0.79 0.39–1.62 0.52 0.70 0.34–1.45 0.34
 LAVI 0.99 0.97–1.01 0.38 0.98 0.97–1.00 0.081
 CHA2DS2-VASc ≥4 1.32 1.16–1.49 <0.001 1.49 1.27–1.75 <0.001
 CKD 0.65 0.41–1.01 0.057 0.87 0.54–1.39 0.55

P values <0.05 (ie, statistically significant differences) are in boldface.

CKD = chronic kidney disease; other abbreviations as in Table 1.