Fig. 5.

PDA-HP/NIR treatment suppresses glial activation and promotes a shift toward anti-inflammatory polarization following SCI. (A) Representative fluorescence images and quantification showing GFAP (green) and IBA1 (red) staining of spinal cord sections in each group. Scale bars are 10 μm. Quantification of mean fluorescence intensity is shown in (B, C). Data are presented as mean ± SD (n = 6, ∗∗∗p < 0.001, and ∗∗∗∗p < 0.0001). (D) Representative fluorescence images and quantification showing Arg-1 (green) and iNOS (red) staining of spinal cord sections in each group. Scale bars are 10 μm. Quantification of mean fluorescence intensity is shown in (E, F). Data are presented as mean ± SD (n = 6, ∗p = 0.011, ∗∗∗p < 0.001, and ∗∗∗∗p < 0.0001). (For interpretation of the references to color in this figure legend, the reader is referred to the Web version of this article.)