Table 3.
Lipoprotein(a)-Associated ORs for Prevalence and Recurrence of Myocardial Infarction
| Analysis | Myocardial Infarction | P Value | STEMI | P Value | Recurrent MI | P Value |
|---|---|---|---|---|---|---|
| Univariate | ||||||
| Lp(a) >230 nmol/L | 1.91 (1.15-3.16) | 0.012 | 2.22 (1.01-4.88) | 0.047 | 13.74 (1.85-101.95) | 0.010 |
| Lp(a), per 100 nmol/L | 1.19 (1.03-1.36) | 0.017 | 1.14 (0.93-1.40) | 0.207 | 1.48 (1.14-1.91) | 0.003 |
| Multivariable modela | ||||||
| Lp(a) >230 nmol/L | 2.02 (1.20-3.39) | 0.008 | 2.34 (1.05-5.21) | 0.037 | 14.21 (1.91-105.81) | 0.010 |
| Lp(a), per 100 nmol/L | 1.23 (1.06-1.43) | 0.006 | 1.18 (0.95-1.46) | 0.127 | 1.57 (1.18-2.07) | 0.002 |
| Multivariable modelb | ||||||
| Lp(a) >230 nmol/L | 1.85 (1.03-3.33) | 0.041 | 2.42 (1.02-5.72) | 0.044 | 15.90 (2.07-122.37) | 0.008 |
| Lp(a), per 100 nmol/L | 1.20 (1.01-1.42) | 0.042 | 1.18 (0.93-1.49) | 0.171 | 1.62 (1.19-2.20) | 0.002 |
Values are OR (95% CI). Myocardial infarction and recurrent MI are defined according to the fourth universal definition of MI. STEMI prevalence was at the time of the first MI.
STEMI = ST-segment elevation myocardial infarction; other abbreviations as in Table 1.
Adjusted for age and sex.
Adjusted for age, sex, diabetes, hypertension, former smoking, total cholesterol (continuous), LDL-C (continuous), HDL-C (continuous), eGFR (continuous), and lipid-lowering therapy.