Fig. 2.

t-SNE plots of subtype patients and proportion who change subtype. Panels A–D illustrate t-distributed stochastic neighbour embedding plots of clinical sepsis subtypes where lighter shaded dots are margin strata and darker shaded dots are core strata. Panels E–H overlap black dots for subtype members who transition to another subtype. Panel I shows the cumulative proportion of patients who transition subtype over 48 h. Green is α-type, purple is β-type, red is γ-type, and blue is δ-type. Light grey are not members of that subtype. Core patients have >90% membership probability for their assigned clinical sepsis subtype, and margin patients have <90% membership probability.