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. 2026 Jan 6;37:102772. doi: 10.1016/j.mtbio.2026.102772

Fig. 9.

Fig. 9

Schematic diagram of nanomaterial design and specific mechanisms for PA/FL dual-mode imaging in RA treatment. (A) Folate Receptor-Targeted NIR-II Dual-Model Nanoprobes for Multiscale Visualisation of Macrophages in Rheumatoid Arthritis. Reprinted from Ref. [35]. Copyright 2023, John Wiley and Sons. (B) Neutrophils-mediated bioinspired nanoagents for noninvasive monitoring of inflammatory recruitment dynamics and navigating phototherapy in rheumatoid arthritis. Reprinted from Ref. [36]. Copyright 2024, Elsevier. (C) A multifunctional nanoaggregate-based system for detection of rheumatoid arthritis via Optoacoustic/NIR-II fluorescent imaging and therapy via inhibiting JAK-STAT/NF-κB/NLRP3 pathways. Reprinted from Ref. [37]. Copyright 2023, John Wiley and Sons. (D) In Vivo Evaluation of Liver Injury and Arthritis Enabled by a Nitroxyl-Activated Near-Infrared Fluorescence and Photoacoustic Dual-Modality Imaging Probe. Reprinted from Ref. [38]. Copyright 2025, American Chemical Society.