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. 2026 Jan 16;15:1677325. doi: 10.3389/fonc.2025.1677325

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Copyright © 2026 Peng, Liu, Li, Chen, Hu and Du.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Three survival analysis graphs (A, B, C) show recurrence-free survival percentages over months of follow-up. Graph A has a blue line. Graph B shows red and blue lines, labeled as extremities and non-extremities, respectively, with a significant log-rank p-value of 0.017. Graph C compares primary and recurrent groups with significant differences, p-value 0.02. — Kaplan-Meier curves for recurrence-free survival (RFS). (A) RFS in the overall cohort. (B) RFS stratified by tumor location (Extremities vs. Non-extremities; Log-rank p = 0.017). (C) RFS stratified by tumor status (Primary vs. Recurrent; Log-rank p = 0.02). All panels: X-axis, follow-up time (months); Y-axis, recurrence-free survival (%).