Table 1.
Comparison of clinicopathological characteristics between abdominal and extra-abdominal desmoid tumors#.
| Characteristic | Total | Abdominal | Extra-abdominal | χ² | P value |
|---|---|---|---|---|---|
| (n=81) | (n=27) | (n=54) | |||
| Gender | |||||
| Male | 27 (33.3) | 11 (40.7) | 16 (29.6) | 1 | 0.317 |
| Female | 54 (66.7) | 16 (59.3) | 38 (70.4) | ||
| Age | |||||
| <40 years | 49 (60.5) | 18 (66.7) | 31 (57.4) | 0.646 | 0.422 |
| ≥40 years | 32 (39.5) | 9 (33.3) | 23 (42.6) | ||
| Symptoms | |||||
| Asymptomatic | 49 (60.5) | 17 (63.0) | 32 (59.3) | 0.103 | 0.748 |
| Symptomatic | 32 (39.5) | 10 (37.0) | 22 (40.7) | ||
| Admission status | |||||
| Primary | 67 (82.7) | 26 (96.3) | 41 (75.9) | 3.897 | 0.048* |
| Recurrent | 14 (17.3) | 1 (3.7) | 13 (24.1) | ||
| Medical history | |||||
| Positive | 24 (29.6) | 12 (44.4) | 12 (22.2) | 4.263 | 0.039* |
| Negative | 57 (70.4) | 15 (55.6) | 42 (77.8) | ||
| Maximum diameter | |||||
| <7cm | 36 (44.4) | 10 (37.0) | 26 (48.1) | 0.9 | 0.343 |
| ≥7cm | 45 (55.6) | 17 (63.0) | 28 (51.9) | ||
| Adjacent to vessels/nerves | |||||
| No | 59 (72.8) | 14 (51.9) | 45 (83.3) | 9.017 | 0.003* |
| Yes | 22 (27.2) | 13 (48.1) | 9 (16.7) | ||
| Single/Multiple | |||||
| Solitary | 78 (96.3) | 26 (96.3) | 52 (96.3) | N/A | N/A |
| Multiple | 3 (3.7) | 1 (3.7) | 2 (3.7) | ||
| Treatment | |||||
| Surgery alone | 68 (84.0) | 25 (92.6) | 43 (79.6) | N/A | N/A |
| Surgery + radiotherapy | 13 (16.0) | 2 (7.4) | 11 (20.4) | ||
| Surgical repair | |||||
| Primary closure | 66 (81.5) | 19 (70.4) | 47 (87.0) | 3.314 | 0.069 |
| Complex repair** | 15 (18.5) | 8 (29.6) | 7 (13.0) | ||
| Mesh reconstruction | 7 (46.7) | 6 (75.0) | 1 (14.3) | ||
| Flap transplantation | 2 (13.3) | 0 | 2 (28.6) | ||
| Flap repair | 4 (26.7) | 0 | 4 (57.1) | ||
| Stoma creation | 2 (13.3) | 2 (25.0) | 0 | ||
| Recurrence status | |||||
| Censored | 58 (71.6) | 25 (92.6) | 33 (61.1) | 8.774 | 0.003* |
| Recurred | 23 (28.4) | 2 (7.4) | 21 (38.9) | ||
| Ki67 index | |||||
| ≥5% | 35 (55.6) | 14 (58.3) | 21 (53.8) | 0.121 | 0.728 |
| <5% | 28 (44.4) | 10 (41.7) | 18 (46.2) | ||
| CD34 | |||||
| Negative | 51 (85.0) | 18 (81.8) | 33 (86.8) | 0.023 | 0.881 |
| Positive | 9 (15.0) | 4 (18.2) | 5 (13.2) | ||
| S100 | |||||
| Negative | 58 (93.5) | 22 (91.7) | 36 (94.7) | N/A | N/A |
| Positive | 4 (6.5) | 2 (8.3) | 2 (5.3) | ||
| Desmin | |||||
| Negative | 24 (47.1) | 8 (44.4) | 16 (48.5) | 0.076 | 0.782 |
| Positive | 27 (52.9) | 10 (55.6) | 17 (51.5) | ||
| SMA | |||||
| Negative | 17 (28.8) | 7 (30.4) | 10 (27.8) | 0.048 | 0.826 |
| Positive | 42 (71.2) | 16 (69.6) | 26 (72.2) | ||
| β-catenin | |||||
| Negative | 3 (5.3) | 0 (0.0) | 3 (8.6) | N/A | N/A |
| Positive | 54 (94.7) | 22 (100.0) | 32 (91.4) | ||
# Data are presented as number of patients (%), χ² test was used for comparison between groups.
* Values in bold denote statistically significant differences (p < 0.05).
** For the subcategories of surgical repair, percentages are calculated based on the number of patients who underwent complex repair in each group (abdominal group: n=8; extra-abdominal group: n=7).