Table 2. Detailed individual characteristics of patients with brain metastasis from ovarian carcinoma (N=7). WBRT: Whole Brain Radiation Therapy; V-P shunt: Ventriculoperitoneal shunt.
| Case Rank (Based on age) |
1 | 2 | 3 | 4 | 5 | 6 | 7 | |
|---|---|---|---|---|---|---|---|---|
| Age at diagnosis (years) | 57 | 45 | 45 | 42 | 39 | 37 | 25 | |
| Presenting symptoms | Headache Behavioral changes | Headache Vomiting Blurred vision |
Unsteady gait | Headache Blurred vision |
Headache Vomiting Blurred vision Weakness |
Headache Blurred vision Unsteady gait |
Headache Vomiting Blurred vision weakness |
|
| Histopathology | Serous High grade |
Serous High grade, papillary |
Serous High grade |
Mucinous High grade |
Mucinous High grade |
Serous High grade, papillary |
Non-gestational Choriocarcinoma (NGCC) | |
| Fertility drug use | No | Yes | No | Yes | Yes | Yes | No | |
| Site of the lesion | Cerebellum | Cerebrum | Cerebellum | Cerebrum | Cerebrum | Cerebellum | Cerebrum | |
| Number of lesions | Solitary | Multiple | Solitary | Solitary | Solitary | Multiple | Solitary | |
| Treatment modalities | Craniotomy for resection of brain lesion | Craniotomy | Only V-P Shunt | Craniotomy | Craniotomy | Craniotomy | Craniotomy + V-P Shunt | Craniotomy |
| Radiotherapy | WBRT | WBRT | WBRT | WBRT | WBRT | WBRT | No | |
| Chemotherapy | Taxol/Carb | Taxol/Carb | Taxol/Carb | Taxol/Carb | Taxol/Carb | Taxol/Carb | Methotrexate | |
| Laparotomy for resection of ovarian carcinoma | Yes | No | Yes | Yes | Yes | Yes | No | |
| Tumor marker | CA 125 178 U/ml |
CA125 280 U/ml |
CA125 161 U/ml |
CA 125 154 U/ml |
CA125 112 U/ml |
CA125 295 U/ml |
B-hCG 40,000 mIU/ml |
|
| Survival (months) | 38 | 18 | 23 | 14 | 24 | 12 | 2 | |