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. Author manuscript; available in PMC: 2026 Feb 1.
Published in final edited form as: Biochemistry. 2026 Jan 2;65(2):137–148. doi: 10.1021/acs.biochem.5c00719

Figure 5.

Figure 5.

Family 2B encapsulin-associated terpene biosynthetic pathways. (A) A representative biosynthetic gene cluster of a PT-associated Family 2B encapsulin from Streptomyces coelicolor. A potential reaction scheme is shown for the production of FPP. Additional putative tailoring enzymes are numbered. (B) The biosynthetic gene cluster for the 2-MIBS-associated Family 2B encapsulin from S. griseus with the reaction scheme for 2-MIB synthesis. (C) A biosynthetic gene cluster from M. xanthus associated with a GS-like TC and a reaction scheme for geosmin biosynthesis. In all panels, genes are color-coded by function. Gray genes are confirmed and or predicted tailoring enzymes.