Table 3.
Univariate and multivariate Cox proportional hazards analysis of overall survival
| Covariables | Value | Number | Univariate | Multivariate | ||
|---|---|---|---|---|---|---|
| Hazard ratio [95% CI] | p value | Hazard ratio [95% CI] | p value | |||
| Age | (Continuous variable) | 1.017 [0.989–1.046] | 0.233 | 0.995 [0.966–1.025] | 0.748 | |
| Gender | Male | 238 | 1 (Reference) | 1 (Reference) | ||
| Female | 45 | 1.282 [0.646–2.547] | 0.478 | 1.339 [0.653–2.746] | 0.426 | |
| Performance status | 0 | 223 | 1 (Reference) | 1 (Reference) | ||
| 1 | 60 | 2.263 [1.287–3.981] | 0.005 | 1.396 [0.774–2.518] | 0.267 | |
| Clinical stage | I–II | 134 | 1 (Reference) | 1 (Reference) | ||
| ≥ III | 149 | 4.721 [2.378–9.373] | < 0.001 | 9.297 [4.014–21.530] | < 0.001 | |
| Chemotherapy | No | 97 | 1 (Reference) | 1 (Reference) | ||
| Yes | 186 | 0.940 [0.539–1.639] | 0.828 | 0.264 [0.124–0.565] | 0.001 | |
| SMA | High | 141 | 1 (Reference) | 1 (Reference) | ||
| Low | 142 | 1.841 [1.071–3.162] | 0.027 | 1.851 [1.070–3.200] | 0.028 | |
SMA skeletal muscle area at the level of the third cervical vertebra