Table 4.
Univariate and multivariate Cox proportional hazards analysis of progression free survival
| Covariables | Value | Number | Univariate | Multivariate | ||
|---|---|---|---|---|---|---|
| Hazard ratio [95% CI] | p value | Hazard ratio [95% CI] | p value | |||
| Age | (Continuous variable) | 0.993 [0.976–1.011] | 0.463 | 0.985 [0.967–1.004] | 0.118 | |
| Gender | Male | 238 | 1 (Reference) | 1 (Reference) | ||
| Female | 45 | 1.054 [0.636–1.747] | 0.840 | 0.968 [0.579–1.618] | 0.900 | |
| Performance status | 0 | 223 | 1 (Reference) | 1 (Reference) | ||
| 1 | 60 | 1.966 [1.302–2.969] | 0.001 | 1.563 [1.021–2.395] | 0.040 | |
| Clinical stage | I–II | 134 | 1 (Reference) | 1 (Reference) | ||
| ≥ III | 149 | 2.405 [1.616–3.577] | < 0.001 | 3.317 [1.996–5.512] | < 0.001 | |
| Chemotherapy | No | 97 | 1 (Reference) | 1 (Reference) | ||
| Yes | 186 | 1.037 [0.701–1.533] | 0.857 | 0.454 [0.269–0.768] | 0.003 | |
| SMA | High | 141 | 1 (Reference) | 1 (Reference) | ||
| Low | 142 | 1.091 [0.751–1.583] | 0.649 | 1.070 [0.736–1.556] | 0.722 | |
SMA skeletal muscle area at the level of the third cervical vertebra