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. 2026 Jan 30;16(1):e110772. doi: 10.1136/bmjopen-2025-110772

Table 2. List of follow-up variables collected in SIGNAL.

Variables Baseline 6 months (FU1) 10 years (FU2)
PROMIS-29
 Physical function x x
 Anxiety x x
 Depression x x
 Fatigue x x
 Sleep disturbance x x
 Social roles and activities x x
 Pain interference x x
 Pain intensity x x
SIS-59
 Strength x x
 Hand function x x
 ADL/IADL x x
 Mobility x x
 Communication x x
 Emotion x x
 Memory and thinking x x
 Social participation x x
Barthel Index
 Bowel x x
 Bladder x x
 Grooming x x
 Toilet use x x
 Feeding x x
 Transfer x x
 Mobility x x
 Dressing x x
 Stairs x x
 Bathing x x
 MOCA x
 FMA x
 TUG x
 ART x
 SPD x

Table showing baseline variables.

ADL, Activities of Daily Living; ART, Aphasia Rapid Test; FMA, Fugl-Meyer Assessment of Motor Recovery; FU, follow-up; IADL, Instrumental Activities of Daily Living; MoCA, Montreal Cognitive Assessment; mRS, modified Rankin Scale; PROMIS-29, The Patient-Reported Outcomes Measurement and Information System-29; SIGNAL, Stroke Investigation Group in North and Central London; SIS-59, Stroke Impact Scale-59; SPD, Spoken Picture Description; TUG, Timed-Up-and-Go.