Table 2.
Demographic and biochemical characteristics of study participants.
| Variable | Control (n = 90) |
All CRC patients (n = 130) |
Early stages (I and II) (n = 45) |
Stage III (n = 45) |
Stage IV (n = 40) |
P-value |
|---|---|---|---|---|---|---|
|
Sex Male Female |
42 (46.7%) 48 (53.3%) |
60 (46.2%) 70 (53.8%) |
18 (40%) 27 (60%) |
23 (51.1%) 22 (48.9%) |
19 (47.5%) 22 (48.9%) |
0.941 |
| Age (years) | 60.9 ± 4.54 | 62.2 ± 4.61 | 60.7 ± 4.8 | 62.9 ± 4.83 | 63.3 ± 4.02* | 0.061 |
| CEA (ng/ml) | 3.16 ± 1.37 | 6.29 ± 2.36* | 4.3 ± 1.38* | 6.79 ± 1.9*¥ | 7.98 ± 2.1*¥# | 0.0001* |
| CA19-9 (U/ml) | 18.9 ± 6.98 | 28 ± 10.66* | 22 ± 7.33* | 29.6 ± 6.84*¥ | 32.9 ± 13.9*¥ | 0.0001* |
CRC: Colorectal cancer; CEA: Carcinoembryonic antigen; CA19-9: Carbohydrate antigen 19 − 9.
Data are expressed as mean (percentage) or mean ± SD.
P-values were calculated by comparing the control group with all CRC patients using either the student’s t-test or the Mann-Whitney U test, as appropriate.
* Significant from control, ¥ Significant from early stages (I and II), # Significant from stage III.