Table 4.
Diagnostic performance of the indices for the differentiation of F3 and F4 from lower stages
|
Indices
|
AUC
|
P value
|
Sensitivity
|
Specificity
|
PPV (%)
|
NPV (%)
|
DA (%)
|
| FIB-4 | 0.806 | 0.000 | 0.692 | 0.804 | 72.97 | 77.36 | 75.63 |
| APRI | 0.772 | 0.000 | 0.820 | 0.627 | 62.75 | 82.05 | 71.21 |
| NLR | 0.540 | 0.512 | 0.462 | 0.706 | 54.55 | 63.16 | 60.00 |
| PLR | 0.301 | 0.001 | 0.051 | 0.980 | 66.67 | 57.47 | 58.43 |
| NPAR | 0.673 | 0.005 | 0.615 | 0.745 | 64.86 | 71.7 | 68.88 |
FIB-4: Fibrosis index based on four factors; APRI: Aspartate transaminase to platelet ratio index; NLR: Neutrophil-lymphocyte ratio; PLR: Platelet-to-lymphocyte ratio; NPAR: Neutrophil percentage-to-albumin ratio; AUC: Area under the curve; PPV: Positive predictive value; NPV: Negative predictive value; DA: Diagnostic accuracy.