Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
Cut-off validation against established thresholds
|
Marker
|
Established cut-off
|
Our cut-off
|
Clinical utility
|
| FIB-4 | > 1.45 (rule-out) | > 1.42 | Equivalent rule-out |
| APRI | > 0.7 (significant) | > 0.68 | Validated threshold |
| PLR | Novel marker | > 142.5 | Exploratory |
| NPAR | Novel marker | > 14.13 | Exploratory |
FIB-4: Fibrosis index based on four factors; APRI: Aspartate transaminase to platelet ratio index; PLR: Platelet-to-lymphocyte ratio; NPAR: Neutrophil percentage-to-albumin ratio.
