Table 2.

Associations between lowest MAP or largest MAP reduction from baseline and AKI

	Unadjusted		Adjusted
	Chi-Square	P value	Chi-Square	P value
Lowest MAP (mmHg)	15.2	0.0005	7.68	0.0215
Largest MAP reduction from baseline (%)	3.36	0.189	1.39	0.4985

Results of univariate (unadjusted) and multivariate (adjusted) logistic regression models with restricted cubic splines were calculated using ANOVA. For multivariate logistic regression models, fixed effects include age, sex, BMI, ASA levels, surgery duration, intraoperative use of phenylephrine or norepinephrine, preoperative use of cephalosporins, penicillins, quinolones, aminoglycosides, or vancomycin, preoperative comorbidities (hypertension, cerebral infarction, cardiac insufficiency, Alzheimer’s disease, Parkinson’s disease), preoperative uric acid and urea, blood loss, crystal volume, plasma substitute, and blood transfusion

AKI Acute kidney injury, MAP Mean arterial pressure