Table 2.
Bile acid profiles in matched serum and follicular fluid (FF) samples (n = 79)
| Serum | FF | ||
|---|---|---|---|
| µmol/l | Median, IQR | Median, IQR | p value |
| CDCA | 0.05 (0.01–0.19) | 0.1 (0.03–0.21) | 1.00 |
| CA | 0 (0–0.06.06) | 0.05 (0–0.12.12) | 0.79 |
| DCA | 0.15 (0.09–0.26) | 0.13 (0.05–0.22) | < 0.001 |
| GCA | 0.01 (0–0.07.07) | 0.03 (0–0.11.11) | 1.00 |
| GCDCA | 0.28 (0.11–0.46) | 0.51 (0.33–0.73) | < 0.001 |
| GDCA | 0.09 (0.02–0.21) | 0.12 (0.05–0.26) | 1.00 |
| GUDCA | 0 (0–0.04.04) | 0 (0–0.05.05) | 1.00 |
| TCA | n.d | n.d. | 0.01 |
| TCDCA | 0.01 (0–0.06.06) | 0.04 (0–0.08.08) | 0.29 |
| TDCA | n.d | 0 (0–0.03.03) | 1.00 |
| TUDCA | n.d | n.d. | 1.00 |
| UDCA | 0.08 (0.02–0.16) | n.d. | < 0.001 |
Values are expressed as median and interquartile range (IQR). To assess differences between paired samples multiple testing using Wilcoxon signed-rank test and Bonferroni-Dunn post-hoc was performed; n.d., not detectable; CDCA, chenodeoxycholic acid; CA, cholic acid; DCA, deoxycholic acid; GCA, glycocholic acid; GCDCA, glycochenodeoxycholic acid; GDCA, glycodeoxycholic acid; GUDCA, glycoursodeoxycholic acid; TCA, taurocholic acid; TCDCA, taurochenodeoxycholic acid; TDCA, taurodeoxycholic acid; TUDCA, tauroursodeoxycholic acid; UDCA, ursodeoxycholic acid