Table 3.
Stratified analysis HRs and 95% CIs for lung cancer by Coffee and Tea intake among 498,043 persons in the UK Biobank study.
| Characteristics | Coffee | Tea | ||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| 0 | 0.5–1 | 2–3 | ≥4 | P interaction | 0 | 0.5–1 | 2–3 | ≥4 | P interaction | |
| Sex | ||||||||||
| Male | Ref | 0.68 (0.58–0.80) | 0.74 (0.64–0.87) | 0.97 (0.83–1.13) | 0.675 | Ref | 0.76 (0.62–0.93) | 0.63 (0.53–0.74) | 0.91 (0.79–1.06) | < 0.001 |
| Female | Ref | 0.77 (0.65–0.91) | 0.80 (0.68–0.95) | 1.13 (0.96–1.33) | Ref | 0.86 (0.70–1.06) | 0.86 (0.70–1.06) | 0.86 (0.70–1.06) | ||
| Age | ||||||||||
| < 65 | Ref | 0.73 (0.64–0.84) | 0.76 (0.67–0.87) | 1.04 (0.91–1.19) | 0.683 | Ref | 0.82 (0.69–0.97) | 0.69 (0.60–0.80) | 0.89 (0.78–1.01) | 0.207 |
| ≥65 | Ref | 0.70 (0.56–0.87) | 0.78 (0.64–0.96) | 1.01 (0.81–1.25) | Ref | 0.77 (0.59–1.00) | 0.63 (0.51–0.79) | 0.78 (0.64–0.95) | ||
| Smoker | ||||||||||
| Never | Ref | 0.89 (0.70–1.13) | 0.93 (0.73–1.17) | 0.78 (0.58–1.04) | < 0.001 | Ref | 1.08 (0.77–1.52) | 1.00 (0.75–1.32) | 1.00 (0.77–1.31) | 0.036 |
| Ever | Ref | 0.67 (0.58–0.77) | 0.75 (0.66–0.85) | 1.26 (1.11–1.42) | Ref | 0.73 (0.62–0.86) | 0.56 (0.49–0.64) | 0.78 (0.70–0.88) | ||
| BMI | ||||||||||
| < 25 | Ref | 0.83 (0.68–1.01) | 0.90 (0.74–1.09) | 1.22 (1.00–1.48) | 0.008 | Ref | 0.85 (0.67–1.07) | 0.58 (0.48–0.71) | 0.76 (0.64–0.91) | 0.950 |
| ≥25 | Ref | 0.68 (0.59–0.78) | 0.72 (0.63–0.82) | 0.94 (0.82–1.08) | Ref | 0.78 (0.65–0.94) | 0.74 (0.64–0.86) | 0.92 (0.81–1.05) | ||
Adjusted for age, sex, race, physical activity, educational level, employment status, smoking, drinking, body mass index, townsend deprivation index, cardiovascular, and cancer. Bold values indicates P < 0.05