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. 2026 Jan 3;6:73. doi: 10.1038/s43856-025-01333-4

Table 1.

Baseline characteristics of the participants stratified by WHRa

Characteristic Overall WHR P
Without abdominal obesity With abdominal obesity
Sample size 88571 46554 42017
Age 55.8 (8.1) 54.8 (8.2) 56.9 (7.8) <0.001
Female 47459 (53.6%) 33618 (72.2%) 13841 (32.9%) <0.001
Deprivation index −1.4 (3.0) −1.6 (2.9) −1.3 (3.1) <0.001
White 84351 (95.2%) 44536 (95.7%) 39815 (94.8%) <0.001
Education level, n (%) <0.001
No qualification 12888 (14.6%) 5370 (11.5%) 7518 (17.9%)
Any other qualification 44854 (50.6%) 23160 (49.7%) 21694 (51.6%)
University degree or above 30829 (34.8%) 18024 (38.7%) 12805 (30.5%)
Dietary score, n (%) <0.001
Meeting <2 targets 42383 (47.9%) 20007 (43.0%) 22376 (53.3%)
Meeting ≥2 targets 46188 (52.1%) 26547 (57.0%) 19641 (46.7%)
Smoking status, n (%) <0.001
Never 49602 (56.0%) 28610 (61.5%) 20992 (50.0%)
Previous 29958 (33.8%) 13874 (29.8%) 16084 (38.3%)
Current 9011 (10.2%) 4070 (8.7%) 4941 (11.8%)
Alcohol intake, n (%) <0.001
Never 3392 (3.8%) 1812 (3.9%) 1580 (3.8%)
Previous 2852 (3.2%) 1430 (3.1%) 1422 (3.4%)
Current, <3 times/week 42321 (47.8%) 22943 (49.3%) 19378 (46.1%)
Current, ≥3 times/week 40006 (45.2%) 20369 (43.8%) 19637 (46.7%)
Regular exercise, n (%) 46664 (52.7%) 25412 (54.6%) 21252 (50.6%) <0.001
eGFR 91.6 (12.8) 92.5 (12.6) 90.6 (13.0) <0.001
Hypertension 46822 (52.9%) 19664 (42.2%) 27158 (64.6%) <0.001
Dyslipidemia 10753 (12.1%) 3623 (7.8%) 7130 (17.0%) <0.001
Type 2 diabetes 3813 (4.3%) 619 (1.3%) 3194 (7.6%) <0.001
Plasma fatty acids
SFAs (% TFA) 34.0 (1.9) 33.7 (1.7) 34.3 (2.1) <0.001
MUFAs (% TFA) 23.4 (2.6) 22.5 (2.3) 24.4 (2.6) <0.001
Total PUFAs (% TFA) 42.6 (3.7) 43.8 (3.1) 41.3 (3.9) <0.001
n-3 PUFAs (% TFA) 4.4 (1.6) 4.5 (1.6) 4.3 (1.5) <0.001
n-6 PUFAs (% TFA) 38.2 (3.6) 39.3 (3.0) 37.0 (3.8) <0.001

aAll variables measured at baseline are presented as mean (SD) or number (%).