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. 2026 Jan 3;6:73. doi: 10.1038/s43856-025-01333-4

Table 3.

Additive interactions of different fatty acids and abdominal obesity on incident MVDsa

Fatty acids RERI AP SI
SFAs 0.02 (−0.09, 0.13) 0.01 (−0.07, 0.10) 1.07 (0.70, 1.63)
MUFAs 0.07 (−0.04, 0.19) 0.06 (−0.03, 0.14) 1.32 (0.79, 2.19)
Total PUFAs 0.00 (−0.10, 0.10) 0.00 (−0.10, 0.10) 1.01 (0.15, 7.07)
n-3 PUFAs −0.14 (−0.25, −0.03) −0.12 (−0.22, −0.03) 0.49 (0.31, 0.79)
n-6 PUFAs 0.00 (−0.10, 0.11) 0.00 (−0.10, 0.10) 1.00 (0.29, 3.45)

aData are presented as the point estimate (95% CI) for the additive interaction metrics. The regression model was adjusted for age, sex, ethnicity, deprivation index, education level, dietary score, alcohol, smoking status, physical activity, eGFR, dyslipidemia, hypertension, and type 2 diabetes. Reference group: participants without abdominal obesity and with fatty acid levels below the median.