Table 1.
Population in Study by |
|||
Hundscheid et al. (2000a) | Murray et al. (2000)a | Vianna-Morgante and Costa (2000)a | |
No. premutation carriers interviewed (age) | 148 (>18 years) | 116 (not specified) | 113 (⩾25 years) |
Median age at examination | 50 years | Not specified | 38 years |
No. pedigrees examined (average no. females/pedigree) | 55 (2.69) | 62 (1.87) | Not specified |
No. PIP/no. MIP/no. unknown [PIP:MIP] | 106/42/not specified [2.52] | 51/40/25 [1.27] | 32/27/54 [1.19] |
No. females ⩾40 years at examination (PIP/MIP) [PIP:MIP] | 82/27 [3.03] | 12/18 [.67] | 15/10 [1.50] |
Ratio of no. females ⩾40 years at examination:no. females <40 years at examination (PIP/MIP) | 3.41/1.80 | .31/.82 | .88/.59 |
Mean age at menopause, for premutation carriersb | 45 years | 48 years | Not done |
% POF among females ⩾40 years (PIP/MIP) | 28%/4% | 17%/28% | 33%/20% |
In this issue of the Journal.
Estimated using survival analysis.