Table 3.
Segregation Analysis of EC under Model 2 (Type Influences Susceptibility)
|
Hypothesis |
|||||||
| Mendelian |
Environmental |
||||||
| Parametera | Dominant | Recessive | Codominant | No Major Type | τ’s Equal | τ’s = q | General |
| qA | .0121 | .1767 | .1755 | … | .6476 | .5560 | .1913 |
| τAA | 1.0b | 1.0b | 1.0b | … | .5067 | .5560c | 1d |
| τAB | .5b | .5b | .5b | … | .5067c | .5560c | .4830 |
| τBB | 0b | 0b | 0b | … | .5067c | .5560c | .0383 |
| β | −10.3680 | −10.2019 | −10.2100 | −10.4262 | −10.5727 | −10.4256 | −10.3353 |
| α | .1676 | .1640 | .1642 | .1684 | .1697 | .1684 | .1662 |
| γAA | .7391 | 1d | 1d | .0945 | 0d | .3056 | 1d |
| γAB | .7391c | .0265 | .0289 | .0945c | 0d | 0d | 0d |
| γBB | .0387 | .0265c | .0258 | .0945c | .5527 | 0d | .0259 |
| χ2 | 5.76 | 1 | 1 | 83.13 | 67.83 | 86.13 | … |
| df | 1–4 | 2–4 | 1–3 | 3–6 | 1–4 | 2–3 | … |
| P value | .01<P<.3 | .5<P<.95 | .3<P<.9 | <.001 | <.001 | <.001 | … |
| −2lnL | 1819.73 | 1814.97 | 1814.97 | 1900.10 | 1881.80 | 1900.10 | 1813.97 |
| AIC | 1829.73 | 1824.97 | 1826.97 | 1906.10 | 1895.80 | 1912.10 | 1831.97 |
a
See Materials and Methods for definitions of the parameters.
b
Parameter is fixed at this value and is not estimated.
c
Parameter is constrained to equal the preceding one and is not estimated.
d
Parameter estimate went to bound.