Skip to main content

View full-text article in PMC

. 2000 Jun 6;67(1):110–119. doi: 10.1086/302970

Table 5.

Segregation Analysis of EC, Incorporating Familial-Effect Covariates

	Hypothesis
	Model 1				Model 2
Parameter^a	Recessive	No Major Type	τ’s Equal	General	Recessive	No Major Type	τ’s Equal	General
q_A	.3325	…	.0311	.2677	.1736	…	.6043	.8580
τ_AA	1.0^b	…	.3326	1^c	1.0^b	…	.3207	1^c
τ_AB	.5^b	…	.3326^d	.0645	.5^b	…	.3207^d	.5136
τ_BB	0^b	…	.3326^d	.4786	0^b	…	.3207^d	.0745
β_AA	−10.8163	−11.2618	−6.3085	−10.5457	−10.5859	−11.2618	−10.3926	−10.6515
β_AB	−56.6500	−11.2618^d	−11.7224	−61.5000	−10.5859^d	−11.2618^d	−10.3926^d	−10.6515^d
β_BB	−56.6500^d	−11.2618^d	−71.7000	−54.7800	−10.5859^d	−11.2618^d	−10.3926^d	−10.6515^d
ξ_S1	-.0213	.1931	.1547	−.1776	−.2023	.1931	.1131	−.1270
ξ_S2	.4576	.7137	.8179	.4285	.4287	.7137	.7073	.5070
ξ_F1	.0492	.3844	−1.0750	−.6005	−.3428	.6704	.2905	−.4834
ξ_F2	−.1623	−.2955	−2.6694	−.6363	−.2983	−.0095	−.6864	−.3947
ξ_M1	.1128	1.3642	−2.4742	−.0452	.0535	1.0781	.3746	−.4034
ξ_M2	−.0499	.5229	−3.4406	.0757	.0808	.2369	−.4958	−.1020
ξ_OS1	.2266	.4925	2.1263	.3205	.1096	.4925	.6885	.2170
ξ_OS2	.0640	.0193	−.1268	.0606	.0903	.0193	−.0117	.0859
α	.1691	.1629	.1818	.1687	.1668	.1629	.1609	.1692
γ_AA	.4706	.1070	1^c	.6639	1^c	.1070	0^c	1^c
γ_AB	.4706^d	.1070^d	1^d	.6639^d	.0268	.1070^d	0^c	0^c
γ_BB	.4706^d	.1070^d	1^d	.6639^d	.0268^d	.1070^d	.4003	.0195
χ²	10.39	73.39	41.30	…	2.85	75.18	49.41	…
df	3–4	5–6	2	…	2–4	3–6	1–2	…
P value	.01<P<.05	<.001	<.001	…	.2<P<.7	<.001	<.001	…
−2lnL	1820.77	1883.77	1851.68	1810.38	1811.44	1883.77	1858.00	1808.59
AIC	1846.77	1905.77	1881.68	1844.38	1837.44	1905.77	1888.00	1842.59

^a

See Material and Methods for definitions of the parameters.

^b

Parameter is fixed at this value and is not estimated.

^c

Parameter estimate went to bound.

^d

Parameter is constrained to equal the preceding one and is not estimated.