Table 6.
Power Simulations Based on 1,000 Replicates of 100 Nuclear Families Including One Parent and One Affected Offspring
|
Power |
||
| Model | LRAT | TRANSMIT |
| Dominant: | ||
| E10D5: | ||
| 1.2 | .062 | .050 |
| 1.4 | .083 | .063 |
| 1.6 | .097 | .082 |
| 1.8 | .168 | .144 |
| 2.0 | .216 | .183 |
| E25D10: | ||
| 1.2 | .074 | .070 |
| 1.4 | .126 | .110 |
| 1.6 | .199 | .183 |
| 1.8 | .325 | .313 |
| 2.0 | .454 | .441 |
| E50D15: | ||
| 1.2 | .105 | .102 |
| 1.4 | .256 | .254 |
| 1.6 | .515 | .515 |
| 1.8 | .783 | .786 |
| 2.0 | .922 | .923 |
| Recessive: | ||
| E10R5: | ||
| 1.2 | .108 | .090 |
| 1.4 | .142 | .124 |
| 1.6 | .272 | .245 |
| 1.8 | .447 | .397 |
| 2.0 | .598 | .557 |
| E25R10: | ||
| 1.2 | .121 | .114 |
| 1.4 | .400 | .386 |
| 1.6 | .627 | .620 |
| 1.8 | .868 | .866 |
| 2.0 | .970 | .967 |
| E50R15: | ||
| 1.2 | .338 | .337 |
| 1.4 | .871 | .873 |
| 1.6 | .998 | .998 |
| 1.8 | 1.000 | 1.000 |
| 2.0 | 1.000 | 1.000 |