Table 3.
Estimates of Power for Four Different Tests with Nominal Significance Level .05, on the Basis of 5,000 Replicates of 250 Extended Pedigrees
|
Estimated Power of |
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| Model | No. of Affected Sibs per Pedigree | Sib-TDTa | Sib-TDTb | Tspb | PDT |
| 1 | 4.5 | .6626 | .4814 | .6042 | .9064 |
| 2 | 4.5 | .4348 | .2816 | .3788 | .6764 |
| 3 | 4.5 | .2408 | .1600 | .1972 | .3960 |
| 4 | 2.5 | .7538 | .6240 | .7264 | .8996 |
| 5 | 2.5 | .4480 | .3420 | .4270 | .5944 |
| 6 | 2.5 | .1172 | .1018 | .1198 | .1616 |
a
Sampling the most genotypically different DSP from each pedigree.
b
Sampling a single nuclear family/sibship randomly from each pedigree.