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Pedigree drawings. A, Family 1; B, family 2; C, family 3; D, family 4; and E, family 5. Black shading of the left half of symbols indicates hand and foot abnormalities. Gray shading of the right half of symbols indicates genital abnormalities (hypospadias or other penile abnormality in males; uterine and/or vaginal abnormalities in females). An asterisk (*) above a symbol indicates that the individual had a urinary tract abnormality on diagnostic imaging.
