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Ratios of day 8 AUC0-24 to day 1 AUC0-24 for total ertapenem
| Panel | Dose (g) | N | Geometric mean AUC0-24 on day:
|
AUC GMR day 8/day 1 | 90% CI of AUC GMR | |
|---|---|---|---|---|---|---|
| 1 | 8 | |||||
| A | 0.25 | 6 | 148.36 | 151.43 | 1.02 | 0.97, 1.07 |
| B | 0.5 | 6 | 274.76 | 293.41 | 1.07 | 0.92, 1.24 |
| C | 1 | 6 | 480.70 | 501.44 | 1.04 | 0.98, 1.11 |
| D | 2 | 6 | 1,041.67 | 1,019.30 | 0.98 | 0.89, 1.08 |
| E | 3 | 6 | 1,547.55 | 1,266.06 | 0.82 | 0.76, 0.88 |
