Table 2.

NRAMP1 Haplotypes

		Haplotype
Marker	Location in NRAMP1	1	2	3	4	5
(GT)na,b,c	5′ Promoter region	286	286	288	288	286
77−385C/Td	5′ Promoter region	C	T	C	C	C
274C/Ta	Codon 66, exon 3	C	C	T	C	C
469+14G/Ca,c	Intron 4	G	G	C	G	G
577−18G/Aa	Intron 5	G	G	G	G	G
823C/Ta	Codon 249, exon 8	C	C	C	T	T
A318Va	Codon 318, exon 9	Ala	Ala	Ala	Ala	Ala
1465−85G/Aa	Intron 13	G	G	A	A	A
D543Na,c	Codon 543, exon 15	Asp	Asn	Asp	Asn	Asn
(CAAA)ne	3′ UTR	2	3	3	3	3

^aName of variant as defined by Liu et al. (1995a); the nucleotides and codons were numbered according to the sequence of GenBank accession number L32185.

^bMicrosatellite alleles are designated by size (in bp), SNPs by nucleotides, coding variants by amino acids, and the insertion/deletion polymorphism by number of repeat units.

^cMarker used in the case-control study of western Africans, by Bellamy et al. (1998).

^dSNP (Lewis et al. 1996) nucleotide 129 (see GenBank accession number U57604) or nucleotide 3247 (see GenBank accession number D63507), which is 385 bp preceding the A (nucleotide 77; see GenBank accession number L32185) in the initiation codon.

^eInsertion/deletion–polymorphism (Buu et al. 1995) nucleotides 1993–2000 (see GenBank accession number L32185) and nucleotides 269–280 (see GenBank accession number U26447).