TABLE 2.

K_m values of wild-type and mutant HIV-1 RT enzymes

HIV-1 RT	Km (μM)a
	dATP	dGTP
Wild type	0.333	0.172
K65R	0.392	0.254b
K65R+M184V	0.554c	0.314c

^aK_m values are averages for multiple experiments, with an average standard error of 0.063 for dATP and 0.03 for dGTP.

^bP ≤ 0.05 compared to the K_m for the wild type by two-tailed Student's t test.

^cP ≤ 0.01 a compared to the K_m for the wild type by two-tailed Student's t test.