TABLE 3.

Frequency of selection of resistant mutants of strain ISP794

Concn (μg/ml) of selecting drug	Factor of MIC of selecting drug		Frequency of selection of mutants
	Garenoxacin	Ciprofloxacin	Garenoxacin	Ciprofloxacin
0.032	1		;@0017>2.0 × 10−5-3.6 × 10−5
0.064	2		<7.4 × 10−12-4.0 × 10−11
0.128	4		<7.4 × 10−12
0.5		2		2.8 × 10−6-1.5 × 10−5
1.0		4		3.0 × 10−8-6.1 × 10−8
2.0		8		<4.5 × 10−11-2.8 × 10−9