TABLE 5.
Hemolytic activities of antimicrobial peptides in rabbit and human erythrocytes
| Peptide | Rabbit RBC (% lysis)a at:
|
Human RBC (% lysis) at:
|
||
|---|---|---|---|---|
| 200 μM | 50 μM | 200 μM | 50 μM | |
| S25 | 3 | 0 | 0 | 0 |
| A25 | 1 | 0 | ND | ND |
| F25 | 4 | 0 | 1 | 0 |
| F25-6K | ND | ND | 17 | 11 |
| 4F | 34 | 14 | 42 | 17 |
| F21 | 3 | 1 | 0 | 0 |
| F17 | 2 | 0 | 0 | 0 |
| F17-R | 2 | 0 | 0 | 0 |
| F17-6K | 1 | 0 | 0 | 0 |
| All-d F17-6K | 2 | 0 | 0 | 0 |
| F17-6R | 3 | 1 | 26 | 14 |
| KAFW | 1 | 0 | 0 | 0 |
| 3F176K | 2 | 0 | 0 | 0 |
| W17-6K | 2 | 0 | 0 | 0 |
a
RBC, red blood cells. Percentages are given to the nearest 0.5%. Values are representative of two to three experiments. ND, not determined.