FIG. 6.

Survival of B6D2F₁/J mice treated with macrolide antimicrobial agents (50 mg of AZM/kg p.o. or s.c., 150 mg of CLR/kg p.o., 500 mg of ERY/kg p.o., and 20 mg of TVA/kg p.o.) for 14 days after ⁶⁰Co γ irradiation (7 Gy) and challenge with B. anthracis Sterne spores (1.8 × 10⁸ CFU i.t.). Therapy was started 24 h after challenge and continued for 14 days. Significant comparisons were as follows: ERY versus TVA (P = 0.0001).