Figure 1.

Dependence of the sperm flagella movement on the activity of the mitochondrial oxidative phosphorylation complexes. The activity of several mitochondrial OXPHOS complexes was inhibited by increasing concentrations of the indicated drug, and the proportion of sperm cells able to move following a quick and straight trajectory (open circles) or that manifest any kind of flagella activity (close circles) was evaluated after 3 min in the presence of the drug by microscopy count in a Neubauer chamber. Data represent average ± standard error of the mean (SEM) of four independent experiments.