Table 4.
The ZIP synergy scores of concomitant açaí extract and anticancer drug combinations provided by SynergyFinder Plus.
| MCF-7 (ER+) | MDA-MB-231 (ER−) | MCF-10A (normal) | ||||
|---|---|---|---|---|---|---|
| EXTRACT | MTX | TAM | MTX | TAM | MTX | TAM |
| Methanol Extract of Fruit Powder from Brazil (MRME) | 2.22 Additive |
7.68 Additive |
7.22 Additive |
−1.79 Additive |
16.75
Synergistic |
−1.36 Additive |
| Aqueous Extract of Fruit Powder from Brazil (MRAQ) | 8.98 Additive |
9.44 Additive |
- | - | - | - |
| Acidic Methanol Extract of Brand #2 Supplement (F4AC) | 8.95 Additive |
6.31 Additive |
- | - |
23.04
Synergistic |
10.35
Synergistic |
| Acidic Methanol Extract of Brand #1 Supplement (F3AC) | - | - | 7.08 Additive |
0.37 Additive |
10.2
Synergistic |
6.26 Additive |
| Methanol Extract of Brand #2 Supplement (F4ME) | - | - | 4.64 Additive |
−0.14 Additive |
- | - |
Values greater than 10 are considered synergistic, less than −10 are antagonistic, and between −10 and 10 are considered additive. The hyphen indicates combinations that were not tested for those cell lines.