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Linezolid concentrations in serum after administration of single doses of 20 and 80 mg/kg in neutropenic infected mice. Symbols: □, data obtained with the 20-mg/kg dose; ○, data obtained with the 80-mg/kg dose. Each symbol represents the geometric mean ± standard deviation of the levels in the sera of three mice. t1/2, serum elimination half-live in hours; Cmax, peak level in serum; AUC0−∞, serum AUC.
