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Relationships between the percentage of the dosing interval that levels in serum remained above the MIC for S. pneumoniae ATCC 10813, the 24-h AUC/MIC, and the peak/MIC and the log10 number of CFU/thigh after 24 h of therapy. Each symbol represents the data for two mice. The lines represent the best fit line. R2 is the coefficient of determination.
