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Polar release of SARS-CoV following apical application to airway epitheliaa
| Virion egress type | Egress value (PFU/ml) for specimen no.:
|
||
|---|---|---|---|
| 1 | 2 | 3 | |
| Apical | 2.5 × 104 | 5 × 104 | 3 × 104 |
| Basolateral | 15 | 20 | 5 |
Urbani strain SARS-CoV at an MOI of 0.8 was applied to the apical surface of well-differentiated epithelia from three different human donors. Virion egress was assayed 24 h later by determining the titers for Vero E6 cells.
