Table 2.

Grading recommendations.

Items	Definitions
Recommendation
1A	Strong recommendation, high-quality evidence
1B	Strong recommendation, moderate-quality evidence
1C	Strong recommendation, low-quality evidence
2A	Weak recommendation, high-quality evidence
2B	Weak recommendation, moderate-quality evidence
2C	Weak recommendation, low-quality evidence
Quality of evidence
A (High quality)	Robustly designed RCTs
B (Moderate quality)	RCTs with limitations; large-scale, multiple, or methodologically robust observational studies
C (Low quality)	Limited observational studies, small case series, or expert consensus in the absence of substantial empirical data

RCT: Randomized controlled trial.