FIG. 2.

Amino acid alignment of CypA proteins derived from sequences of original or retrotransposed CypA copies from New World monkeys (NWM) and representative species of OWP. Dots represent amino acid identities, whereas asterisks denote stop codons. Residues that are conserved among Aotus species (or NWM) are boxed in white, whereas residues which differ between the retrotransposed and the original CypA copy are boxed in gray. Residues which are known to interact with HIV-1 capsid or with cyclosporine are depicted by arrows.