Table 2. Risk factors for progression-free survival based on univariate and multivariate analysis.

Factors	Univariate analysis				Multivariate analysis
	P value	HR	95% CI		P value	HR	95% CI
Gender
Male	0.046	2.642	1.018, 6.763		0.14	2.086	0.782, 5.565
Female			Reference				Reference
Age (years)
<65	0.006	2.771	1.348, 5.696		0.002	3.305	1.573, 6.945
≥65			Reference				Reference
Smoking
Yes	0.46	1.331	0.623, 2.845		–	–	–
No			Reference
Drinking
Yes	0.43	0.563	0.135, 2.350		–	–	–
No			Reference
Family history
Yes	0.40	2.567	0.550, 4.463		–	–	–
No			Reference
Disease staging
III	0.08	0.426	0.167, 1.092		–	–	–
IV			Reference
Group
AM	0.04	0.507	0.263, 0.978		0.03	0.448	0.218, 0.921
PM			Reference				Reference

CI, confidence interval; HR, hazard ratio.