FIG. 3.

Comparison of CYP sequences. A multiple sequence alignment was generated with the AlignX program of Vector NTI 7 using the 17 Ema and 8 Cyp proteins identified in this study, and their nearest homologs in the databanks. The alignment was graphically rendered as a half-rooted tree with Phylodraw, version 0.8 (http://pearl.cs.pusan.ac.kr/phylodraw/) using the neighbor-joining matrix. Proteins labeled Ema are the biocatalytically active CYPs, and proteins labeled Cyp are the CYP homologs identified in this study. All other CYPs are labeled with their GenBank number. The root node is labeled with a dot. The newly established CYP107Z subfamily is highlighted by a gray oval.