TABLE 1.
Relation between partitioning of several organic compounds in octanol/water (log P), membrane/buffer, water solubility, and the maximum concentration in the membrane
Organic compound | log Po/wa | log Pm/bb | Pm/bb | Solubilityc (mM) | MMCd (mM) | Adaptability |
---|---|---|---|---|---|---|
1-Butanol | 0.89 | 0.21 | 1.6 | 970.0 | 1,586 | − |
1-Hexanol | 1.87 | 1.17 | 14.8 | 56.9 | 841 | − |
Toluene | 2.48 | 1.76 | 57.5 | 6.3 | 368 | + |
1-Octanol | 2.92 | 2.19 | 154.9 | 3.8 | 588 | +/− |
1-Decanol | 3.97 | 3.21 | 1,621.8 | 0.23 | 379 | + |
1-Dodecanol | 5.02 | 4.23 | 16,982.4 | 0.015 | 254 | + |
1-Tetradecanol | 6.07 | 5.25 | 177,827.9 | 0.0008 | 142 | + |