FIG. 4.
Phylogeny of ZntA-like and CopA-like sequences from archaeal genomes. (A) Neighbor-joining analysis of 16S rRNA gene (left) and PIB-type ATPase (right) sequences. Circles at each node indicate the level of bootstrap support obtained when analysis was by both parsimony and distance methods (see the legend to Fig. 2). Instances of incongruence between the two trees are indicated by black ovals. (B) Neighbor-joining analysis of select ZntA-like PIB-type ATPases belonging to both the bacterial and archaeal domains. Evidence supporting a single interdomain gene transfer is boxed and marked with a black oval.