TABLE 3.

Intracellular accumulation of SQV in patients receiving hard-gel versus soft-gel formulations of the drug

Patient no.	Capsule form	AUC0-24 (ng · h ml−1)		Intracellular/plasma drug concn ratio
		Plasma	Intracellular
35	Hard gel	16,038	27,480	1.71
36	Hard gel	1,821	5,370	2.95
39	Hard gel	1,060	13,620	12.85
40	Hard gel	1,815	40,000	22.03
51	Hard gel	1,781	31,380	17.62
53	Hard gel	147	6,180	42.04
54	Hard gel	1,833	34,995	19.09
2	Soft gel	5,450	36,676	6.73
3	Soft gel	3,190	26,340	8.26
13	Soft gel	4,384	18,320	4.18
14	Soft gel	57,876	159,936	2.76
41	Soft gel	3,614	34,140	9.45
52	Soft gel	22,910	301,060	13.14