TABLE 3.

Characteristics of clinical serial C. neoformans isolates from India^a

Patient no.	Strains	Days apart	Source of sample	Change in pattern of:		Change in MIC
				CHEF	RFLP	FLU	AMB
1	I51, I52	d-1	CSF	No change	No change	16, 16	0.125
2	I55, I56, I60	d-3, d-45	CSF	III, III, IV	B, C, G	32, 32, 16	0.25
3	I57, I59	d-27	CSF	VII, VI	G, B	8	0.06, 0.25
4	I61, I63	d-7	CSF	No change	A, B	8, 16	0.25
5	I66, I73	d-131	CSF	IX, I	No change	32, 16	0.25, 0.5
6	I68, I74	d-99	CSF	XIII, II	No change	16, 32	0.125, 0.5
7	I82, I83	d-1	Blood, urine	No change	No change	16, 8	0.125, 0.06
8	I88, I90	d-14	CSF	ND	ND	2, 4	0.125
9	I91, I95, I96	d-6, d-15	CSF	No change	No change	16, 32, 16	0.125
10	I107, I110, I111, I112	d-8, d-8, d-13	CSF, urine	No change	C, D, C, C	8, 4, 4, 8	0.06, 0.125
11	I108, I109	d-2	CSF	No change	No change	8, 16	0.5
12	I114, I117	d-4	CSF	X, I	O, A	32	0.06, 0.125
13	I120, I121	d-5	CSF, blood	No change	No change	8, 16	0.125
14	I126, I129	d-18	CSF	No change	No change	8	0.125

^ad, day; ND, not determined; FLU, fluconazole; AMB, amphotericin B.