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. 2002 Oct;46(10):3334–3336. doi: 10.1128/AAC.46.10.3334-3336.2002

TABLE 1.

Correlation of linezolid resistance levels with percentage of mutated 23S rRNA genesa

Enterococcal strain Linezolid MIC (μg/ml) No. of mutated genes/total no. of 23S genes (%)
E. faecium LS-1 2 0/6 (0)
E. faecium LR-6 8 1/6 (17)
E. faecium LR-9 16 1/6 (17)
E. faecium LR-1 32 2/6 (33)
E. faecium LR-3 32 2/6 (33)
E. faecium LR-5 32 2/6 (33)
E. faecium LR-8 32 3/6 (50)
E. faecium LR-7 64 4/6 (67)
E. faecium LR-4 64 5/6 (83)
E. faecalis LR-2 128 4/4 (100)
a

Detected by sequencing (or MaeI digestion) of PCR-amplified 23S rRNA genes.